Senior Research Fellow
Mr. Ribhav Mishra: I finished Master of Science in Biomedical Sciences from University of Applied Sciences, Bonn Rhien Sieg, Germany and further did a 8 month research project at University of Bonn, Germany in the domains of protein biochemistry. Thus, I have a genuine interest to work in the field of protein biochemistry and in future would work to understand the role of protein misfolding in various pathological conditions. I joined IITJ in August 2014 as a PhD student and will like to explore the functions of E3 ubiquitin ligases in regulating the cellular protein homeostasis.
Deepak Chhangani- PHD from Cellular and Molecular Neurobiology Lab (IIT Jodhpur) : Presently Post Doctoral Fellow, McKnight Brain Institute, University of Florida. Previously I did Masters of Biotechnology from MN Institute of Applied Sciences, Bikaner. I always wanted to understand the most basic aspects of life, hence, taken life sciences as my subject to study. Currently, I am working with proteins quality control mechanisms and intended to pursue further research in ageing and age related diseases. Scopus Champion of IIT Jodhpur: Genetic materials of cells express their functionality through their end products, the polypeptide chains which essentially, are to be folded in their proper conformations in order to perform their functions. Cells contain a system that maintains functional protein pool, is called “Protein Quality Control System”. We investigated the protein quality control mechanism and decipher the role of E3 ligases. We reviewed various strategies of E3 ubiquitin ligases how they target misfolded proteins for their degradation, and how E3 ligases and chaperones together confer cytoprotection through various proteolytic pathways. Moreover, we reported a novel role of an E3 ubiquitin ligase Mahogunin Ring Finger 1 (MGRN1) as Quality Control E3 ubiquitin ligases (QCE3s). MGRN1 can interact with Hsp70 chaperone, and hereby may take advantage to recognize the misfolded proteins and promote their degradation. This work led me to have the title of “Scopus Champion” of IIT Jodhpur.
Mr. Arun Kumar Upadhyay: PHD from Cellular and Molecular Neurobiology Lab (IIT Jodhpur) : Presently “Assistant Professor” in “Central University of Rajasthan” India. I have done my graduation (B.Sc. Honors) in Zoology from Hans Raj College, University of Delhi. After that I was selected through JNU CBEE for MSc. Biotechnology program of University of Lucknow. Meanwhile I have qualified CSIR JRF examination and later selected for PhD program in IIT Jodhpur. Now I am doing research in Cellular and Molecular Neurobiology Laboratory.
Ms. Vibhuti Joshi: PHD from Cellular and Molecular Neurobiology Lab (IIT Jodhpur) : I joined IITJ in July 2013 as a Ph.D student after completing M.Sc. and B.Sc. Biotechnolgy from MLS University Udaipur,Rajasthan.I was awarded Summer research fellowship from Indian Academy of Sciences during M.Sc. and Junior Research Fellowship from CSIR. During my M.Sc. project I worked on ihpRNAi construct formation against viruses. Here I am working on cancer and E3 ubiquitin ligases. I belive that” The measure of greatness in a scientific idea is the extent to which it stimulates thought and opens up new lines of research.”
Mr. Ayeman Amanullah: I completed my B.Tech and M.Tech integrated degree in Biotechnology and Bioinformatics from Centre for Converging technologies, University of Rajasthan. I joined this lab as a PhD student in year 2013. My interest lies in exploring the exciting area of protein quality control mechanism and its importance in cellular system.