Obtaining Human Microglia from Adult Human Brain Tissue

Ishan Agrawal, Shivanjali Saxena, Preethika Nair, Deepak Jha, Sushmita Jha
[JOVE]

Mitochondrial Dysfunction and Alzheimer’s Disease: Role of Microglia

Ishan Agrawal, Sushmita Jha
[Frontiers in Aging Neuroscience]

Comprehensive review of ASC structure and function in immune homeostasis and disease

Ishan Agrawal, Sushmita Jha
[Molecular Biology Reports, Springer]

Portable, low‐cost hypoxia chamber for simulating hypoxic environments: Development, characterization and applications

Shivanjali Saxena, Ishan Agrawal, Pratibha Singh, Sushmita Jha
[Medical Devices & Sensors, Wiley Publishing Group]

Differential Expression Profile of NLRs and AIM2 in Glioma and Implications for NLRP12 in Glioblastoma

Nidhi Sharma, Shivanjali Saxena, Ishan Agrawal, Shalini Singh, Varsha Srinivasan, S. Arvind, Sridhar Epari, Sushmita Paul, Sushmita Jha
[Scientific Reports, Nature Publishing Group]

Patent

Hypoxia chamber for simulating hypoxic environment to study hypoxia related diseases specially cancer. (Patent application number : 201811017208)

S Saxena, S Jha

Book Chapter

Invited Book Chapter for American society for Microbiology, titled “Myeloid cells in health and disease: a synthesis”, Editor: Siamon Gordon, University of Oxford, Commissioning editor: Greg Payne, American Society for Microbiology, Publisher ASM Press

S Jha, WJ Brickey and JPY Ting

[ISBN 1555819184, 9781555819187]

NLRs as Helpline in the Brain: Mechanisms and Therapeutic Implications

S Singh, S Jha ^{Corresponding Author}
[PubMed][Molecular Neurobiology]

Evaluation of wound dressing properties of chitin membranes containing nanosilver

R Singh, K Shitiz, S Singh, S Jha, A Singh
[Biomedical Physics & Engineering Express]

A role for the NLR family members NLRC4 and NLRP3 in sterile inflammasome activation in glial cells

H Guo, L Freeman, CN David, WJ Brickey, S Jha, JP Ting
[The Journal of Immunology]

NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes

L Freeman, H Guo, CN David, WJ Brickey, S Jha, JPY Ting
[PubMed][Journal of Experimental Medicine]

Role of NOD-like Receptors in Glioma Angiogenesis: Insights into future therapeutic interventions

S Saxena, S Jha ^{Corresponding Author}
[PubMed][Cytokine & growth factor reviews]

NLRC3 mediated PI3K-mTOR inhibition takes a toll on colon cancer

N Sharma, S Jha ^{Corresponding Author}
[Translational Cancer Research]

Trigonella seed extract ameliorates inflammation via regulation of the inflammasome adaptor protein, ASC

S Jha ^{Corresponding Author}, N Sharma, S Suresh, A Debnath
[PubMed][Frontiers in Bioscience]

Inflammasomes in Myeloid Cells: Warriors within

S Jha, WJ Brickey, JPY Ting
[PubMed][Microbiology spectrum]

NLR-regulated pathways in cancer: opportunities and obstacles for therapeutic interventions

N Sharma, S Jha ^{Corresponding Author}
[PubMed][Cellular and Molecular Life Sciences]

Holding the inflammatory system in check: NLRs keep it cool

S Jha, JPY Ting
[PubMed]

Novel approach for security in wireless sensor network using bio-inspirations

H Rathore, V Badarla, S Jha, A Gupta
[Communication Systems and Networks]

Bio-inspired machine learning based wireless sensor network security

H Rathore, S Jha
[Nature and Biologically Inspired Computing]

MyD88 provides a protective role in long-term radiation-induced lung injury

WJ Brickey, IP Neuringer, W Walton, X Hua, EY Wang, S Jha, GD Sempowski, X Yang, SL Kirby, SL Tilley, JPY Ting
[PubMed][International journal of radiation biology]

Plexin-B2 negatively regulates macrophage motility, Rac, and Cdc42 activation

KE Roney, BP O'Connor, HWen, EK Holl, EH Guthrie, BK Davis, SW Jones, S Jha, L Sharek, R Garcia-Mata, JE Bear, JPY Ting
[PubMed][PLoS One]

Plexin-D1 is a novel regulator of germinal centers and humoral immune responses

EK Holl, BP O’Connor, TM Holl, KE Roney, AG Zimmermann, S Jha, G Kelsoe, JPY Ting
[PubMed][The Journal of Immunology]

Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

H Wen, D Gris, Y Lei, S Jha, L Zhang, MTH Huang, WJ Brickey, JPY Ting
[PubMed][Nature immunology]

Recombinant human interleukin-11 treatment enhances collateral vessel growth after femoral artery ligation

J Aitsebaomo, S Srivastava, H Zhang, S Jha, Z Wang, S Winnik, AN Veleva, X Pi, P Lockyer, JE Faber, C Patterson
[PubMed][Arteriosclerosis, thrombosis, and vascular biology]

The inflammasome sensor, NLRP3, regulates CNS inflammation and demyelination via caspase-1 and interleukin-18

S Jha, SY Srivastava, WJ Brickey, H Iocca, A Toews, JP Morrison, VS Chen, D Gris, GK Matsushima, JPY Ting
[PubMed][Journal of Neuroscience]

Inflammasome-associated nucleotide-binding domain, leucine-rich repeat proteins and inflammatory diseases

S Jha, JPY Ting
[PubMed][The Journal of Immunology]